发明名称 |
MODULATION OF REACTIVATION OF A LATENT VIRUS |
摘要 |
The disclosure relates to methods of controlling the state of a virus (lytic or lysogenic) in an individual, such as a method of reactivating a latent virus in an individual, comprising administering one or more agents that modulates the activity of signal transducer and activator of transcription 3 (STAT3) or any of p300, CBP or p300/CBP. Also contemplated are methods further comprising administering an HDAC modulating agent, such as an HDAC inhibiting agent or an HDAC activating agent. |
申请公布号 |
WO2014185973(A3) |
申请公布日期 |
2015.01.22 |
申请号 |
WO2014US00110 |
申请日期 |
2014.05.14 |
申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
ROIZMAN, BERNARD;ZHOU, GUOYING;DU, TE |
分类号 |
A61K38/00;A01N37/18;C12N5/00;C12N5/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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