发明名称 USE OF SUBSTITUTED DIPHENYLAMINE COMPOUNDS IN PREPARING ANTI-TUMOUR DRUGS
摘要 The invention relates to substituted diphenylamine compounds using as antitumor agents. The structure of the compounds is represented as the general formula (I): The groups are as defined as specification. The compound represented by formula (I) showed potent antitumor activity, especially to cure or alleviate the cancer causing by cancer cells of human tissue or organ. The preferred cancers are: colon cancer, liver cancer, lymph cancer, lung cancer, esophageal cancer, breast cancer, central nervous system cancer, melanoma, ovarian cancer, cervical cancer, renal cancer, leukemia, prostatic cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharynx cancer or stomach cancer.
申请公布号 EP2826474(A1) 申请公布日期 2015.01.21
申请号 EP20130761044 申请日期 2013.03.06
申请人 SINOCHEM CORPORATION;SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. 发明人 LIU, CHANGLING;CHAI, BAOSHAN;LI, HUICHAO;GUAN, AIYING
分类号 A61K31/136;A61K31/277;A61P35/00;C07C205/06;C07C205/37;C07C211/55;C07C211/56;C07C217/92;C07C229/58;C07C233/65;C07C255/57;C07C255/58;C07C255/59;C07C323/36;C07D213/643 主分类号 A61K31/136
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