发明名称 |
OXAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE |
摘要 |
Novel 2,4-oxazolidinedione compounds of the formula: <IMG> wherein R is a hydrocarbon residue or a heterocyclic group each of which may be substituted; Y is -CO-, -CH(OH)- or -NR3- (wherein R3 is an alkyl group which may be substituted); m is 0 or 1; n is 0, 1 or 2; X is CH or N; A is bivalent straight or branched hydrocarbon chain residue having 1 to 7 carbon atoms; R1 and R2 each are hydrogen or an alkyl group, or R1 and R2 are combined with each other to form a 5- to 6-membered heterocyclic group optionally containing nitrogen; L and M each are hydrogen, or L and M are combined with each other to form a bond, or pharmaceutically acceptable salts thereof, having excellent hypoglycemic and hypolipidemic activities and are useful as antidiabetics or hypolipidemic agents.
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申请公布号 |
CA2116387(A1) |
申请公布日期 |
1994.08.27 |
申请号 |
CA19942116387 |
申请日期 |
1994.02.24 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SOHDA, TAKASHI;IKEDA, HITOSHI;MOMOSE, YU;IMAI, SACHIKO |
分类号 |
C07D491/048;A61K31/42;A61K31/421;A61K31/422;A61K31/425;A61K31/427;A61K31/435;A61K31/44;A61K31/4439;A61K31/47;A61K31/4709;A61K31/535;A61K31/5377;A61P3/06;A61P3/08;A61P3/10;A61P9/12;A61P43/00;C07D263/44;C07D277/22;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D491/052;C07D498/04;(IPC1-7):C07D413/06;C07D473/00;C07D475/00;C07D471/04;C07D487/04;C07D417/06;A61K31/41;A61K31/495 |
主分类号 |
C07D491/048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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