发明名称 OXAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE
摘要 Novel 2,4-oxazolidinedione compounds of the formula: <IMG> wherein R is a hydrocarbon residue or a heterocyclic group each of which may be substituted; Y is -CO-, -CH(OH)- or -NR3- (wherein R3 is an alkyl group which may be substituted); m is 0 or 1; n is 0, 1 or 2; X is CH or N; A is bivalent straight or branched hydrocarbon chain residue having 1 to 7 carbon atoms; R1 and R2 each are hydrogen or an alkyl group, or R1 and R2 are combined with each other to form a 5- to 6-membered heterocyclic group optionally containing nitrogen; L and M each are hydrogen, or L and M are combined with each other to form a bond, or pharmaceutically acceptable salts thereof, having excellent hypoglycemic and hypolipidemic activities and are useful as antidiabetics or hypolipidemic agents.
申请公布号 CA2116387(A1) 申请公布日期 1994.08.27
申请号 CA19942116387 申请日期 1994.02.24
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 SOHDA, TAKASHI;IKEDA, HITOSHI;MOMOSE, YU;IMAI, SACHIKO
分类号 C07D491/048;A61K31/42;A61K31/421;A61K31/422;A61K31/425;A61K31/427;A61K31/435;A61K31/44;A61K31/4439;A61K31/47;A61K31/4709;A61K31/535;A61K31/5377;A61P3/06;A61P3/08;A61P3/10;A61P9/12;A61P43/00;C07D263/44;C07D277/22;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D491/052;C07D498/04;(IPC1-7):C07D413/06;C07D473/00;C07D475/00;C07D471/04;C07D487/04;C07D417/06;A61K31/41;A61K31/495 主分类号 C07D491/048
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