| 发明名称 |
THERAPEUTIC ANTIBODIES AND USES THEREOF |
| 摘要 |
Provided herein are methods, compositions, and uses relating to inhibitors of stem cell factor. For example, provided herein are antibodies targeting stem cell factor and methods for treating fibrotic and tissue remodeling diseases. |
| 申请公布号 |
US2015018408(A1) |
申请公布日期 |
2015.01.15 |
| 申请号 |
US201414328024 |
申请日期 |
2014.07.10 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
Lukacs Nicholas W.;Kunkel Steven L.;Hogaboam Cory |
| 分类号 |
C07K16/24;C07K16/46 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated recombinant monoclonal anti-stem cell factor (SCF) antibody comprising: (a) a light chain variable domain comprising the amino acid sequence of SEQ ID NO:4 or sequences with at least 80% identity to SEQ ID NO:4; and (b) a heavy chain variable domain comprising the amino acid sequence of SEQ ID NO:2 or sequences with at least 80% identity to SEQ ID NO:2. |
| 地址 |
Ann Arbor MI US |
