发明名称 MRI造影能を有する重合体−金属錯体複合体、並びにそれを用いたMRI造影用及び/又は抗腫瘍用組成物
摘要 <p>The present invention provides a polymer-metal complex composite, which comprises a block copolymer capable of serving as a constituent member of a polymeric micelle and a metal complex having MRI contrast ability, accumulates in a tumor-specific manner, achieves high image contrast even in a small amount, and has reduced side effects and a long retention time in blood. The polymer-metal complex composite of the present invention comprises a block copolymer (A) represented by general formula (a) and a metal complex (B) having MRI contrast ability, wherein the composite comprises a structure in which a carboxyl anion of poly(carbo) in the copolymer (A) is attached to the metal complex (B) via a metal atom (M).</p>
申请公布号 JP5651468(B2) 申请公布日期 2015.01.14
申请号 JP20100518083 申请日期 2009.06.26
申请人 发明人
分类号 C08G81/00;A61K9/107;A61K33/24;A61K33/26;A61K33/32;A61K33/34;A61K47/32;A61K47/34;A61K47/42;A61K49/00;A61P35/00 主分类号 C08G81/00
代理机构 代理人
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