Contains no O-acetyl groups detectable by NMR and binds to antibodies to S.aureus further conjugated with Pseudomonas aeruginosa exotoxin A as an immunocarrier to detect S.aureus infection

摘要

A negatively-charged S. aureus antigen contains beta-hexosamine as a major carbohydrate component S. aureus strains that carry the antigen account for nearly all of the clinically significant strains of S. aureus that are not Type 5 or Type 8 strains. The antigen can be used in combination with S. aureus Type 5 polysaccharide antigen and S. aureus Type 8 polysaccharide antigen to provide nearly 100% coverage of S. aureus infection.