<p>The present invention provides arrays comprising polypeptides associated with extracellular matrix that can be used to isolate, differentiate, or culture certain cell types including stem cells, cancer cells, and/or primary hepatocytes. The array comprises at least a pair of polypeptides that comprise a polypeptide associated with extracellular matrix or functional fragments thereof. The invention also provides for methods of diagnosing and/or prognosing a certain disease or disorder through contacting a cell sample from a patient with an array comprising at least a pair of polypeptides that comprise a polypeptide sequence associated with extracellular matrix or functional fragments thereof.</p>
申请公布号
EP2823035(A1)
申请公布日期
2015.01.14
申请号
EP20130757657
申请日期
2013.03.11
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人
BHATIA, SANGEETA N.;MALTA, DAVID FERNANDES BRAGA;RETICKER-FLYNN, NATHAN EDWARD;UNDERHILL, GREGORY H.;SCHWARTZ, ROBERT EDWARD