| 发明名称 |
Use of Nanoexpression to Interrogate Antigen Repertoires |
| 摘要 |
Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence. |
| 申请公布号 |
US2015011405(A1) |
申请公布日期 |
2015.01.08 |
| 申请号 |
US201414319489 |
申请日期 |
2014.06.30 |
| 申请人 |
Atreca, Inc. |
发明人 |
DeFalco Jeff;Serafini Tito;Volkmuth Wayne |
| 分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence. |
| 地址 |
San Carlos CA US |
