主权项 |
1. A method of impeding or treating neurodegenerative diseases selected from Alzheimer's disease, mild cognitive impairment, Huntington's disease, Parkinson's disease, Creutzfeldt-Jakob disease, Alexander disease, cognitive and/or psychomotor deficits, ataxias, dementias, cerebrovascular diseases, amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), as well as diseases associated with aging, pathological processes associated with age and progeria, which comprises the administration to a patient needing such treatment, of a therapeutically effective amount of at least a compound of formula (I): where: R1 is selected from alkyl, OH, O-alkyl, SH, S-alkyl, NH2, NH-alkyl, N(alkyl)2 and halogen, R2, R3 and R4 are selected independently from hydrogen, alkyl, OH, O-alkyl, SH, S-alkyl, NH2, NH-alkyl, N(alkyl)2 and halogen, or R1 and R2 and/or R3 and R4 form an —O-alkylene-O— group, or a pharmaceutically acceptable salt or solvate thereof. |