发明名称 APPLICATION OF ALBIZZIA CHINENSIS EXTRACT IN PREPARATION OF MEDICINE FOR TREATMENT OF GASTRIC ULCER
摘要 The present invention discloses an Albizzia chinensis extract used in the preparation of a drug for the treatment of gastric ulcers. Specifically, it discloses an Albizzia chinensis (Osbeck) Merr extract and its preparation method including the stems bark of Albizzia chinensis was successively grounded, extracted, concentrated and purificated, as well as a pharmaceutical composition comprising the Albizzia chinensis extract. Through pharmacological test, it has been demonstrated that, the Albizzia chinensis extract showed strong inhibition activity against proton pumps, and it can be used for the treatment of gastric ulcers, chronic gastritis and other acid-related diseases, and its anti-ulcer effect is significant, quick, safe and reliable.
申请公布号 US2015010664(A1) 申请公布日期 2015.01.08
申请号 US201214353926 申请日期 2012.10.24
申请人 Institute of Materia Medica, Chinese Academy of Medical Sciences 发明人 Yu Shishan;Zhang Jianjun;Ma Shuanggang;Xu Ruiming;Ji Chengxue
分类号 A61K36/48 主分类号 A61K36/48
代理机构 代理人
主权项 1. A preparation method of an Albizzia chinensis (Osbeck) Merr extract comprising the steps of: A. the medicinal material of Albizzia chinensis (Osbeck) Merr is extracted by a solvent; and B. an Albizzia chinensis extract is obtained by using of polyamide column chromatography eluted with a gradient of solvents.
地址 Beijing CN