发明名称 |
METHOD FOR REDUCTION OF 1->3 READING FRAME SHIFTS |
摘要 |
Herein is reported a method for the recombinant production of a polypeptide, which comprises the tripeptide QKK, characterized in that the method comprises the step of recovering the polypeptide from the cells or the cultivation medium of a cultivation of a cell comprising a nucleic acid encoding the polypeptide and thereby producing the polypeptide, whereby the tripeptide QKK comprised in the polypeptide is encoded by the oligonucleotide cag aaa aaa or the oligonucleotide caa aag aaa. |
申请公布号 |
EP2820039(A1) |
申请公布日期 |
2015.01.07 |
申请号 |
EP20130705814 |
申请日期 |
2013.02.26 |
申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
GROSSMANN, ADELBERT;HESSE, FRIEDERIKE;KOPETZKI, ERHARD;LAU, WILMA;SCHANTZ, CHRISTIAN |
分类号 |
C07K14/775;C12N15/67 |
主分类号 |
C07K14/775 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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