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具有下述结构通式的紫草素四聚体类化合物, <img file="FDA0000552833670000011.GIF" wi="632" he="1153" />其中,R<sub>1</sub>=(R)OCOCH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>2</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>3</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>4</sub>=H;或,R<sub>1</sub>=(R)OCOCH<sub>3</sub>,R<sub>2</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>3</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>4</sub>=H;或,R<sub>1</sub>=(S)OCOCH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>2</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>3</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>4</sub>=H;或,R<sub>1</sub>=(S)OH,R<sub>2</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>3</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>4</sub>=H;或,R<sub>1</sub>=(S)OH,R<sub>2</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>3</sub>=H,R<sub>4</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>;或,R<sub>1</sub>=(R)OH,R<sub>2</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>3</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>4</sub>=H;或,R<sub>1</sub>=(R)OH,R<sub>2</sub>=CH<sub>2</sub>CH<sub>3</sub>,R<sub>3</sub>=CH<sub>2</sub>CH=C(CH<sub>3</sub>)<sub>2</sub>,R<sub>4</sub>=H。 |