| 摘要 |
The compounds of Formula (I),;
wherein R1, R2, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, the stereoisomers of the compounds and the salts thereof are effective inhibitors of the type 5 phosphodiesterase. |
| 主权项 |
1. A compound of formula (I)wherein
R1 is —CH2-3-4C-cycloalkyl, R2 is hydrogen, R21 is hydrogen, R22 is hydrogen, halogen, 1-4C-alkyl, 1-4C-alkoxy, —C(O)-1-4C-alkyl or 1-4C-fluoroalkyl, or R21 and R22 combine to form a group —O—CH2—O—, R23 is hydrogen, halogen or 1-4C-alkoxy, R24 is hydrogen, Y is —(CH2)n—, n is 0, R3 is a cyclohexyl or cyclopentyl group substituted by R6 and optionally substituted by R61, R6 is —NH—C(O)—R7, R61 is halogen or 1-4C-alkyl, R7 is 1-4C-alkyl, which is optionally substituted by R71, or R7 is 1-4C-alkoxy, R71 is 1-4C-alkoxy, or a salt thereof, a stereoisomer of the compound or a salt of the stereoisomer. |
