发明名称 |
METHOD FOR DETERMINING RHEUMATOID ARTHRITIS ACTIVITY INDICATOR, AND BIOMARKER USED THEREIN |
摘要 |
<p>The object of the invention is to find a simple biomarker with high reproducibility with regard to a method for evaluating the activity of the condition and progression of rheumatoid arthritis disease and provide an effective evaluation method therefor. The invention is to provide a method for determining the value of a rheumatoid arthritis-linked indicator in a subject, the method being characterized by comprising a step for measuring the amount of expression of the FAM20A gene in blood collected from the subject, a step for analyzing the measured amount of expression using a gene expression profile that is prepared in advance and correlates with the indicator and a step for estimating the value of the indicator in the subject on the basis of the analysis results.</p> |
申请公布号 |
EP2818546(A1) |
申请公布日期 |
2014.12.31 |
申请号 |
EP20110875955 |
申请日期 |
2011.11.17 |
申请人 |
DNA CHIP RESEARCH INC.;KEIO UNIVERSITY;SAITAMA MEDICAL UNIVERSITY |
发明人 |
TAKEUCHI, TSUTOMU;AMANO, KOICHI;ISHIZAWA, YOHEI;NAKAMURA, SEIJI;TANINO, MOTOHIKO;HATA, YUKO |
分类号 |
C12N15/09;C12M1/00;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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