发明名称 |
CARDIAC GLYCOSIDE ANALOGS AND THEIR USE IN METHODS FOR INHIBITION OF VIRAL INFECTION |
摘要 |
The present invention provides methods for inhibition of human herpes virus replication in a subject comprising administering to the subject a therapeutically effective amount of a pharmaceutically acceptable composition comprising a cardiac glycoside analog, including for example, a digitoxin analog and pharmaceutically acceptable carrier. Other methods of the present invention include administering a digitoxin analog along with at least one other biologically active compound and pharmaceutically acceptable carrier. Methods for inhibition of the α3 subtype of the Na/K ATPase in a subject comprising administering to the subject a therapeutically effective amount of a pharmaceutically acceptable composition comprising a digitoxin analog are also provided. |
申请公布号 |
WO2014209507(A1) |
申请公布日期 |
2014.12.31 |
申请号 |
WO2014US37674 |
申请日期 |
2014.05.12 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
BOGER, RAVIT |
分类号 |
A61K31/56;A61K31/58;A61P31/00;A61P31/12 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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