Method and apparatus for performing diffusion spectrum imaging

摘要

A method of generating a magnetic resonance (MR) image of a tissue includes acquiring MR signals at undersampled q-space encoding locations for a plurality of q-space locations that is less than an entirety of the q-space locations sampled at the Nyquist rate, wherein the acquired signal at the q-space locations represents the three-dimensional displacement distribution of the spins in the imaging voxel, synthesizing the MR signal for the entirety of q-space encodings using a compressed sensing technique for a portion of q-space locations at which MR data was not acquired, combining the acquired MR signals at q-space encodings and the synthesized MR signals at q-space encodings to generate a set of MR signals at q-space encodings that are evenly distributed in q-space, using the set of MR signals at q-space encodings to generate a function that represents a displacement probability distribution function of the set of spins in the imaging voxel, and generating an image of the tissue based on at least a portion of the generated function. A system and computer readable medium are also described herein.

主权项

1. A method of generating a magnetic resonance (MR) image of a tissue, said method comprising:
acquiring MR signals at undersampled q-space locations for a plurality of q-space locations that is less than an entirety of the q-space locations, wherein the acquired signal at the q-space locations represents the three-dimensional displacement distribution of the spins in the imaging voxel; synthesizing q-space encodings using a compressed sensing technique for a portion of q-space locations at which MR signals were not acquired; combining the acquired q-space encodings and the synthesized q-space encodings to generate a set of q-space encodings that are evenly distributed in q-space; using the set of q-space encodings to generate a function that represents a distribution of the set of q-space encodings; and generating an image of the tissue based on at least a portion of the generated function;further comprising, inducing a population of polarized spins in the tissue to produce a set of nuclear magnetic resonance (NMR) signals, wherein the signals comprise a set of non-uniformly distributed encodings to measure the three-dimensional displacement probability distribution function of the spins in the tissue.