| 摘要 |
A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. A composition containing a calixarene-based peptide mimetic such as compound 27, compound 40, or the bridged derivative of compound 4, as shown below, is described: (see compound 40), (see compound 27), and (see compound 4). Methods of use and methods of designing calixarene-based peptide mimetics are also described. |
