| 发明名称 |
METHODS OF THERAPEUTIC MONITORING OF PHENYLACETIC ACID PRODRUGS |
| 摘要 |
The present disclosure provides methods for adjusting the dosage of PAA prodrugs (e.g., HPN-100, PBA) based on measurement of PAA and PAGN in plasma and calculating the PAA:PAGN ratio so as to determine whether PAA to PAGN conversion is saturated. |
| 申请公布号 |
SG11201406745V(A) |
申请公布日期 |
2014.12.30 |
| 申请号 |
SG11201406745V |
申请日期 |
2012.09.11 |
| 申请人 |
HYPERION THERAPEUTICS, INC. |
发明人 |
SCHARSCHMIDT, BRUCE;MOKHTARANI, MASOUD |
| 分类号 |
A61K31/216;A61K31/185 |
主分类号 |
A61K31/216 |
| 代理机构 |
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