| 发明名称 |
STABILIZED GLUCAGON NANOEMULSIONS |
| 摘要 |
The present invention provides an oil-in-water nanoemulsion containing glucagon, an oily phase, and an aqueous phase, wherein the glucagon is physically and chemically stable and the nanoemulsion is suitable for administration by manual injection or by a pump to treat hypoglycemia. |
| 申请公布号 |
US2014378381(A1) |
申请公布日期 |
2014.12.25 |
| 申请号 |
US201414315212 |
申请日期 |
2014.06.25 |
| 申请人 |
LATITUDE PHARMACEUTICALS, INC. |
发明人 |
Chen Andrew Xian;Orida Norman Keith;Chen Hailiang;Dang Hau Huu |
| 分类号 |
A61K9/107;A61K47/26;A61K47/18;A61K47/20;A61K38/26;A61K47/24 |
主分类号 |
A61K9/107 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An oil-in-water nanoemulsion composition comprising:
glucagon, an oily phase, and an aqueous phase, wherein the glucagon is not aggregated and retains no less than 75% of its concentration after 3-7 days storage at 37° C., and wherein the oily phase is in the form of oil droplets having a mean diameter of less than about 200 nm. |
| 地址 |
San Diego CA US |
