发明名称 OLIGOMER-NITROIMIDAZOLE ANTI-INFECTIVE CONJUGATES
摘要 The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.
申请公布号 US2014378520(A1) 申请公布日期 2014.12.25
申请号 US201414477606 申请日期 2014.09.04
申请人 NEKTAR THERAPEUTICS 发明人 Ren Zhongxu;Riggs-Sauthier Jennifer;Bentley Michael D.
分类号 C07D233/94 主分类号 C07D233/94
代理机构 代理人
主权项 1. A method for treating a Giardia intestinalis-infected patient, the method comprising administering a therapeutically effective amount of a compound having the following structure: wherein: (a) is 2 or 3;each instance of R1 is hydrogen;each instance of R2 is hydrogen;R3 is selected from the group consisting of hydrogen, methyl and ethyl; and(n) is an integer of from 3 to 7 inclusive.
地址 San Francisco CA US