发明名称 |
OLIGOMER-NITROIMIDAZOLE ANTI-INFECTIVE CONJUGATES |
摘要 |
The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. |
申请公布号 |
US2014378520(A1) |
申请公布日期 |
2014.12.25 |
申请号 |
US201414477606 |
申请日期 |
2014.09.04 |
申请人 |
NEKTAR THERAPEUTICS |
发明人 |
Ren Zhongxu;Riggs-Sauthier Jennifer;Bentley Michael D. |
分类号 |
C07D233/94 |
主分类号 |
C07D233/94 |
代理机构 |
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代理人 |
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主权项 |
1. A method for treating a Giardia intestinalis-infected patient, the method comprising administering a therapeutically effective amount of a compound having the following structure: wherein:
(a) is 2 or 3;each instance of R1 is hydrogen;each instance of R2 is hydrogen;R3 is selected from the group consisting of hydrogen, methyl and ethyl; and(n) is an integer of from 3 to 7 inclusive. |
地址 |
San Francisco CA US |