发明名称 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS
摘要 The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
申请公布号 US2014378453(A1) 申请公布日期 2014.12.25
申请号 US201414317755 申请日期 2014.06.27
申请人 PHARMACYCLICS, INC. 发明人 KOLESNIKOV Aleksandr;RAI Roopa;SHRADER William Dvorak;TORKELSON Steven M.;WESSON Kieron E.;YOUNG Wendy B.
分类号 C07D235/18;C07D401/12;C07D403/10 主分类号 C07D235/18
代理机构 代理人
主权项
地址 Sunnyvale CA US