| 摘要 |
<p>Provided is a method for producing a vesicle composition having an aqueous phase as a continuous phase, containing: an oil phase-preparation step for dissolving an oil phase containing components (A) to (D) at a temperature of equal to or higher than melting point of the oil phase, the components (A) to (D) being: the component (A): a fatty acid of total carbon number of from 12 to 40; the component (B): a tertiary amine compound of total carbon number of from 8 to 75; the component (C): an organic acid of total carbon number of from 1 to 10; and the component (D): the first polyol, an emulsification step for adding the aqueous phase to the oil phase obtained in the oil phase-preparation step while being mixed; an addition step for adding a component (D'): the second polyol, after a quantity of the aqueous phase added to the oil phase is equal to or larger than 1 time by mass of a quantity of the oil phase; and a cooling step for cooling the obtained composition after the emulsification step.</p> |
