| 发明名称 |
FORMULATION FOR ANTI-α4β7 ANTIBODY |
| 摘要 |
<p>Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.</p> |
| 申请公布号 |
KR20140145952(A) |
申请公布日期 |
2014.12.24 |
| 申请号 |
KR20137031205 |
申请日期 |
2012.05.02 |
| 申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
DILUZIO WILLOW;NGUYEN PHUONG M.;VARGA CSANAD M.;PALANIAPPAN VAITHIANATHAN;BROWN JASON;FOX IRVING H.;SCHOLZ CATHERINE;JENKINS HELEN;ROSARIO MARIA |
| 分类号 |
A61K9/08;A61K39/395;A61K47/12;A61K47/14;A61K47/26 |
主分类号 |
A61K9/08 |
| 代理机构 |
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