发明名称 |
Uses of dpp-iv inhibitors |
摘要 |
Disclosed is the use of a DPP IV inhibitor linagliptin also known as 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3- methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione or 1-[( 4-methyl-quinazolin-2-yl)methyl]-3-methyl-7 -(2-butyn-1-yl)-8-(3-(R)-aminopiperidin-1-yl)-xanthine for preparing a medicament for the therapeutic treatment of a physiological functional disorder heart failure. Also disclosed is the combination of linagliptin with another active for the treatment of type 2 diabetes, pre-diabetes or metabolic syndrome. Examples of the other active includes metformin, telmisartan and glitazone. The dosage of linagliptin is 2.5 mg or 5 mg and the dosage is for oral administration. |
申请公布号 |
NZ609765(A) |
申请公布日期 |
2014.12.24 |
申请号 |
NZ20070609765 |
申请日期 |
2007.05.03 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
DUGI KLAUS;HIMMELSBACH FRANK;MARK MICHAEL |
分类号 |
A61K31/4985;A61K31/522;A61P3/10;A61P9/04 |
主分类号 |
A61K31/4985 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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