Metal nanocomposite, preparation method and use thereof

摘要

The disclosure provides metal nanocomposites including one or more metal nanoparticles having a hydrophobic surface and at least partially enclosed by cationic and hydrophilic polymers. The metal nanocomposites are useful as among others, a contrast agent, a diagnostic composition or a pharmaceutical composition.

主权项

1. A metal nanocomposite comprising one or more metal nanoparticles having a hydrophobic surface; and one or more cationic and hydrophilic polymers associated with the hydrophobic surface;
wherein:
the one or more metal nanoparticles is MnFe2O4;the hydrophobic surface contains an organic surfactant having one or more hydrophobic moieties; andthe one or more cationic and hydrophilic polymers are selected from the group consisting of: polyethyleneimine, polyacrylamide, and polyornithine.