发明名称 |
ANTIHYPOXIC AND HYPOLIPIDEMIC PHARMACEUTICAL AGENT IMPROVING CORONARY AND CEREBRAL BLOOD FLOW |
摘要 |
FIELD: medicine.SUBSTANCE: therapeutically effective amount of ethyl methyl hydroxypyridine succinate and calcium atorvastatin, as well as additives in the form of lactose and magnesium stearate are encapsulated in gelatine. Ethyl methyl hydroxypyridine succinate and magnesium stearate is placed into an inner smaller gelatine capsule inside a main outer gelatine capsule containing atorvastatin, lactose and magnesium strearate. The ingredient ratio in the inner capsule makes, wt %: Ethyl methyl hydroxypyridine succinate 96.2-98.6; magnesium stearate 1.4-3.8, and the ingredient ratio in the outer capsule makes, wt %: calcium atorvastatin 10.0-45.0; lactose 52.0-89.0; magnesium stearate 1.0-3.8.EFFECT: method enables providing the higher pharmaceutical effectiveness of the preparation and prolonging the shelf-life by preventing atorvastatin degradation.3 cl, 3 tbl |
申请公布号 |
RU2536275(C1) |
申请公布日期 |
2014.12.20 |
申请号 |
RU20130136691 |
申请日期 |
2013.08.06 |
申请人 |
STROJAKOVSKIJ VALENTIN MEEROVICH;GUMILEVSKIJ ALEKSEJ SERGEEVICH;VANNARI JURIJ ALEKSANDROVICH |
发明人 |
SIDORIN DMITRIJ NIKOLAEVICH;ROGOVA NATAL'JA VIKTOROVNA;AKISHIN MIKHAIL ALEKSANDROVICH |
分类号 |
A61K31/22;A61K9/48;A61K31/4412;A61P9/10;A61P25/28 |
主分类号 |
A61K31/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|