MICROORGANISM PRODUCING O-PHOSPHOSERINE, AND METHOD FOR PRODUCING L-CYSTEINE OR ITS DERIVATIVES OF O-PHOSPHOSERINE WITH USING IT

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to biochemistry and represents a method for producing cysteine involving culturing a recombinant microorganism with the low activity of endogenous phosphoserin phosphatase (SerB) for producing O-phosphoserin (OPS) and contacting the prepared culture containing OPS, or OPS recovered from the culture with sulphide in the presence of O-phosphoserin sulphhydrilase (OPSS) or a microorganism expressing OPSS for preparing cysteine with the recombinant microorganism representing a recombinant bacteria. The invention refers to preparing a cysteine derivative which provides preparing cysteine as presented above to be transformed into the cysteine derivative.EFFECT: invention enables producing cysteine and its derivative with high efficacy.31 cl, 6 dwg, 35 tbl, 49 ex