发明名称 |
Vaccine vectors and methods of enhancing immune responses |
摘要 |
<p>Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB 1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.</p> |
申请公布号 |
AU2011207331(B2) |
申请公布日期 |
2014.12.18 |
申请号 |
AU20110207331 |
申请日期 |
2011.01.21 |
申请人 |
THE TEXAS A&M UNIVERSITY SYSTEM;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS |
发明人 |
BERGHMAN, LUC;BOTTJE, WALTER;HARGIS, BILLY;LAYTON, SHERRYLL |
分类号 |
A61K39/145 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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