| 发明名称 |
METHOD AND CONSTRUCTS FOR DELIVERING DOUBLE STRANDED RNA tO PEST ORGANISMS |
| 摘要 |
The present invention relates in generally to RNAi and its use in gene silencing. In particular, the present invention relates to methods and constructs for delivering double stranded RNA (dsRNA) to pest organisms. |
| 申请公布号 |
US2014373194(A1) |
申请公布日期 |
2014.12.18 |
| 申请号 |
US201414284556 |
申请日期 |
2014.05.22 |
| 申请人 |
DEVGEN N.V. |
发明人 |
Bogaert Thierry Andre Olivier Eddy;Zwaal Richard;Plaetinck Geert;De Kerpel Jan Octaaf;Kaletta Titus Jan |
| 分类号 |
C12N15/82;A61K48/00 |
主分类号 |
C12N15/82 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An RNA delivery molecule consisting of a polypeptide sequence comprising
i) at least one RNA-binding domain, ii) at least one targeting polypeptide able to bind to a cellular endocytosis and/or transcytosis receptor molecule, and iii) optionally at least one peptide linker for linking the RNA binding domain (i) to the targeting polypeptide (ii). |
| 地址 |
Zwijnaarde BE |
