METHOD OF CALIBRATING ION SIGNALS

摘要

A method of mass or ion mobility spectrometry is disclosed comprising: providing an ion source for generating analyte ions and reference ions; providing a mass analyser or ion mobility separator (IMS); providing an ion trap between the ion source and the mass analyser or IMS; guiding reference ions from the ion source into the ion trap and trapping the reference ions in the ion trap; guiding the analyte ions from the ion source into the mass analyser or IMS, wherein the analyte ions bypass the ion trap; and releasing reference ions from the ion trap into the mass analyser or IMS for analysis.