REGULATORY ELEMENTS AND USES THEREOF

摘要

The present application provides novel regulatory elements including promoter sequences from marine microorganisms. The application further discloses DNA constructs containing these novel regulatory elements; transgenic cells, transgenic non-human organisms, and progeny containing these novel regulatory elements. Methods of modifying, producing, and using the regulatory elements are also disclosed. The regulatory elements disclosed herein are particularly suited for use in Nannochloropsis and other microalgae.

主权项

1. An isolated nucleic acid molecule, comprising:
a) a nucleic acid sequence hybridizing under high stringency conditions to a nucleic acid sequence selected from the group consisting of SEQ ID NO: 1 through SEQ ID NO: 16, a complement thereof or a fragment of either; or b) a nucleic acid sequence exhibiting 70% or greater sequence identity to a nucleic acid sequence selected from the group consisting of SEQ ID NO: 1 through SEQ ID NO: 16, a complement thereof or a fragment of either; or c) a nucleic acid sequence comprising a fragment or a cis-acting element of a nucleic acid sequence according to anyone of the paragraphs (a) or (b).