PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to novel compounds of formula,where values A, R-Rare given in i.1 of the invention formula. Methods of obtaining the formula (I) compound are described.EFFECT: compounds demonstrate an inhibiting activity of the cathepsin enzyme, which makes it possible to use them for the preparation of a pharmaceutical composition and for the preparation of a medication.38 cl, 12 dwg, 495 ex