发明名称 |
NAPADISYLATE SALT OF 5-(2-{[6-(2,2-DIFLUORO-2-PHENYLETHOXY) HEXYL]AMINO}-1-HYDROXYETHYL)-8-HYDROXYQUINOLIN-2(1H)-ONE AS AGONIST OF THE BETA 2 ADRENERGIC RECEPTOR |
摘要 |
<p>The present disclosure relates to crystalline monoapadisylate and/or heminapadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, and pharmaceutically acceptable solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the crystalline monoapadisylate and/or heminapadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, and to methods of treatment comprising these pharmaceutical compositions.</p> |
申请公布号 |
KR20140140651(A) |
申请公布日期 |
2014.12.09 |
申请号 |
KR20147032769 |
申请日期 |
2008.02.08 |
申请人 |
ALMIRALL, S.A. |
发明人 |
PUIG DURAN CARLOS;MOYES VALLS ENRIQUE |
分类号 |
C07D215/26;A61K31/47;A61P11/00 |
主分类号 |
C07D215/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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