| 发明名称 |
CHEMICAL COMPOUNDS |
| 摘要 |
The invention concerns compounds of Formula (I);;or pharmaceutically-acceptable salts thereof, wherein R1 to R5 have any of the meanings defined hereinbefore in the description: processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of cell proliferative disorders. |
| 申请公布号 |
US2014357661(A1) |
申请公布日期 |
2014.12.04 |
| 申请号 |
US201414287332 |
申请日期 |
2014.05.27 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
BRADBURY Robert Hugh;BUTTAR David;DE SAVI Christopher;DONALD Craig Samuel;NORMAN Richard Albert;RABOW Alfred Arthur;CURRIE Gordon Stuart;REDFEARN Heather Marie;AKHTAR Nadim;WILLIAMS Helen Elizabeth;OSBORNE Matthew;YAVARI Neda |
| 分类号 |
A61K31/437;A61K45/06;C07D487/04 |
主分类号 |
A61K31/437 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of the Formula (I)wherein: R1 and R2 are each independently H or F; R3 is H or methyl; andeither:
a) R4 is H and R5 is F; or b) R4 is F and R5 is H;or a pharmaceutically-acceptable salt thereof. |
| 地址 |
Sodertalje SE |
