发明名称 |
Assays, methods and apparatus for assessing RNA disruption |
摘要 |
<p>Various embodiments are described herein related to an assay, method and apparatus for performing an RNA Disruption Assay (RDA) for cellular RNA optionally in response to a cytotoxic treatment such as chemotherapy and/or radiation treatment. The method comprises obtaining at least one electropherogram dataset corresponding to a unique biological sample comprising the cellular RNA at a time point, optionally during or after the treatment; determining values for features from at least two shifted regions of the at least one electropherogram dataset, the shifting being due to the treatment; and optionally determining an RDA score based on a combination of the values of the features.</p> |
申请公布号 |
AU2013252445(A1) |
申请公布日期 |
2014.12.04 |
申请号 |
AU20130252445 |
申请日期 |
2013.04.24 |
申请人 |
RNA DIAGNOSTICS INC. |
发明人 |
PRITZKER, KENNETH;PARISSENTI, AMADEO MARK;PRITZKER, LAURA;ZHU, MU;WANG, XIAOHUI;SANTI, STACEY;NARENDRULA, RASHMI |
分类号 |
C12Q1/68;A61K31/337;A61K31/704;A61P35/00;G06F19/20 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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