发明名称 |
TAMPER RESISTANT DOSAGE FORM WITH BIMODAL RELEASE PROFILE |
摘要 |
The invention relates to a pharmaceutical dosage form comprising: (i) at least one formed segment (S1), which contains a first pharmacologically active ingredient (A1) and provides prolonged release thereof, and (ii) at least one further segment (S2), which contains a second pharmacologically active ingredient (A2) and provides immediate release thereof, wherein the at least one formed segment (S1) exhibits a higher breaking strength than the at least one further segment (S2) and the at least one formed segment (S1) exhibits a breaking strength of more than 500 N. |
申请公布号 |
WO2014191396(A1) |
申请公布日期 |
2014.12.04 |
申请号 |
WO2014EP60925 |
申请日期 |
2014.05.27 |
申请人 |
GRÜNENTHAL GMBH |
发明人 |
BARNSCHEID, LUTZ;GEISSLER, ANJA;SCHWIER, SEBASTIAN;PÄTZ, JANA;WENING, KLAUS;STRAUCH, STEFANIE |
分类号 |
A61K9/22;A61K9/24;A61K31/167;A61K31/485;A61P25/04;A61P29/00 |
主分类号 |
A61K9/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|