AUTOMATED PERCENTAGE OF BREAST DENSITY MEASUREMENTS FOR FULL FIELD DIGITAL MAMMOGRAPHY
摘要
An automated percentage of breast density measure (PDa ) that analyzes signal dependent noise (SDN) based on a wavelet expansion using full field digital mammography (FFDM). A matched case-control dataset is used with images acquired from a specific direct x-ray capture FFDM system. PDa is applied to the raw and clinical display representation images. Transforming (pixel mapping) of the raw image to another representation (raw-transformed) is performed using differential evolution optimization and investigated the influence of lowering the native spatial resolution of the image by a one-half. When controlling for body mass index, the quartile specific ORs for the associations of PDa with breast cancer varied with representation and resolution. PDa is a valid automated breast density measurement for a specific FFDM technology and compares well against PD (operator-assisted or the standard) when applied to either the raw-transformed or clinical display images from this FFDM technology.
申请公布号
WO2014194160(A1)
申请公布日期
2014.12.04
申请号
WO2014US40140
申请日期
2014.05.30
申请人
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.;MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人
HEINE, JOHN, J.;SELLERS, THOMAS, A.;VACHON, CELINE, M.;FOWLER, ERIN, E.