CELLULAR RESPONSE ASSAY FOR BIOFLUID BIOMARKER DISCOVERY AND DETECTION
摘要
The invention provides a method to detect an abnormal condition or disease state by assessing a characteristic response pattern of responder cells to indicators contained in a biological fluid of a subject. A characteristic disease-associated pattern can be obtained by determining the response pattern of responder cells to that of bodily fluids or fractions thereof from subjects known to exhibit a particular abnormal condition optionally comparing said pattern to such pattern elicited by fluids or fractions from normal subjects and identifying elements that differ. The identified elements constitute a characteristic or differential pattern which can then be used to identify the presence or stage of a disease in a test subject.
申请公布号
EP2689025(A4)
申请公布日期
2014.12.03
申请号
EP20120765871
申请日期
2012.03.23
申请人
INSTITUTE FOR SYSTEMS BIOLOGY
发明人
SMITH, JENNIFER JOY;AITCHISON, JOHN DAVID;MILLER, LESLIE RAE