发明名称 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING LFA-1
摘要 The invention relates to compounds of formula I: wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to LFA-1 integrin antagonists to target cells expressing LFA-1.
申请公布号 EP2806897(A1) 申请公布日期 2014.12.03
申请号 EP20130701434 申请日期 2013.01.24
申请人 F.HOFFMANN-LA ROCHE AG 发明人 GOODNOW JR., ROBERT ALAN;HAMILTON, MATTHEW MICHAEL;KOWALCZYK, AGNIESZKA;SIDDURI, ACHYUTHARAO
分类号 A61K47/48;A61P29/00;A61P35/00 主分类号 A61K47/48
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