摘要 |
The present invention relates to method of treating distal gastrointestinal diseases including infections, inflammations and functional motility disorders by oral administration of therapeutic or preventive biologic agent that is released directly to the disease area in the distal ileum, ileacecal junction or colon. The biologic agent may include live or dormant bacteria or other organism, e.g. yeast, or other biologic agent. The delivery vehicle must prevent release of the biologic agent in the upper segments of the gastrointestinal tract where it may lose its potency or decrease in quantity. |