发明名称 (3-METHYLPYRROLIDIN-3-YL)METHYL PYRIDINYL ETHER DERIVATIVES AND THEIR USE AS NK-3 RECEPTOR ANTAGONISTS
摘要 <p>The invention relates to a compound of formula wherein A is defined herein or to pharmaceutically active salts, stereoisomeric forms, including individual diastereoisomers and enantiomers of the compound of formula I as well as racemic and non-racemic mixtures thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).</p>
申请公布号 EP2590963(B1) 申请公布日期 2014.12.03
申请号 EP20110728862 申请日期 2011.07.04
申请人 F.HOFFMANN-LA ROCHE AG 发明人 NETTEKOVEN, MATTHIAS;RATNI, HASANE;VIFIAN, WALTER
分类号 C07D401/12;A61K31/4439;A61P25/00;C07D401/14;C07D405/14;C07D413/14 主分类号 C07D401/12
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