| 发明名称 | Uses of GRS proteins or fragments thereof | ||
| 摘要 | The present invention is related to a anticancer composition comprising full length GRS protein or a fragment thereof, a nucleic acid encoding the GRS protein or a fragment thereof. Since the GRS proteins or fragments thereof have activity to induce apoptosis of cancer cell specifically, a composition comprising the GRS proteins or fragments thereof or a nucleic acid encoding thereof may be useful to treatment of cancer. | ||
| 申请公布号 | US8901081(B2) | 申请公布日期 | 2014.12.02 |
| 申请号 | US200913123522 | 申请日期 | 2009.10.12 |
| 申请人 | SNU R&DB Foundation | 发明人 | Kim Sunghoon;Park Min Chul |
| 分类号 | C07K1/00;A61K38/24;A61K38/27;A61K38/00;A61K38/53 | 主分类号 | C07K1/00 |
| 代理机构 | Edwards Wildman Palmer LLP | 代理人 | Edwards Wildman Palmer LLP ;Kim Kongsik;Emmons Richard B. |
| 主权项 | 1. A method for treating cancer comprising a step of administering to a subject in need thereof a pro-apoptotically effective amount of a polypeptide consisting of the amino acid sequence set forth in SEQ ID NO: 6. | ||
| 地址 | Seoul KR | ||