发明名称 Polypeptide or polypeptide construct comprising at least one single domain antibody directed against von willebrand factor, a composition comprising it, a nucleic acid encoding it and uses thereof in the preparation of a medicament for prevention and/or alleviation of conditions of platelet-mediated aggregation
摘要 <p>Provided is a polypeptide or polypeptide construct comprising a) at least one single domain antibody directed against von Willebrand Factor (vWF), b) and, at least one single domain antibody directed against serum albumin (SA), with a specified sequence or a homologous sequence with a sequence identity of more than 70%. Further provided are corresponding nucleic acid sequences. The polypeptides can be used for treatment of conditions of platelet mediated aggregation, including thrombus formation, hyperplasia and lack of patency of diseased arteries. (62) Divided Out of 540771</p>
申请公布号 IL218091(A) 申请公布日期 2014.11.30
申请号 IL20120218091 申请日期 2012.02.14
申请人 ABLYNX NV 发明人
分类号 A61K;A61P;C07K;C12N 主分类号 A61K
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