摘要 |
<p>Provided is a polypeptide or polypeptide construct comprising a) at least one single domain antibody directed against von Willebrand Factor (vWF), b) and, at least one single domain antibody directed against serum albumin (SA), with a specified sequence or a homologous sequence with a sequence identity of more than 70%. Further provided are corresponding nucleic acid sequences. The polypeptides can be used for treatment of conditions of platelet mediated aggregation, including thrombus formation, hyperplasia and lack of patency of diseased arteries. (62) Divided Out of 540771</p> |