发明名称 6-{2-[l-(6-METHYL-3-PYRIDAZINYL)-4-PIPERIDINYL]ETHOXY}-3-ETHOXY-1,2-BENZISOXAZOLE BIS(DIHYDROGENPHOSPHATE) SALT (1:2), METHOD FOR PRODUCTION THEREOF, AND USE THEREOF IN A COMPOSITION AND METHOD OF TREATING OR PREVENTING PICORNAVIRUS INFECTIONS
摘要 This invention relates to antiviral agents, in particular to 6-{2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis(dihydrogenphosphate) salt (1:2), useful in the treatment of infections caused by Picornaviridae, such as human rhinovirus (HRV) and methods for their preparation. The invention also relates to the use of these salts in the treatment of picornavirus infections. The salts of this invention are especially suitable for the treatment of HRV, however it is to be understood that the invention is also applicable to other viruses of the picornavirus family.
申请公布号 EA020455(B1) 申请公布日期 2014.11.28
申请号 EA20100001835 申请日期 2009.05.27
申请人 BIOTA SCIENTIFIC MANAGEMENT PTY LTD. 发明人 RYAN JANE;BUTT MARGARET, ANNE
分类号 C07D413/14;A61K31/423;A61K31/444;A61K31/50;A61P31/16 主分类号 C07D413/14
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