发明名称 HUMAN BINDING MOLECULES HAVING KILLING ACTIVITY AGAINST STAPHYLOCOCCI AND USES THEREOF
摘要 PROBLEM TO BE SOLVED: To provide monoclonal antibodies having opsonic phagocytic killing activity against at least two different Staphylococcus species, and against at least three different strains of Staphylococcus aureus.SOLUTION: Described are human monoclonal antibodies specifically binding to staphylococci and having killing activity against staphylococci, nucleic acids encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the human binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment resulting from staphylococci.
申请公布号 JP2014221060(A) 申请公布日期 2014.11.27
申请号 JP20140136049 申请日期 2014.07.01
申请人 CRUCELL HOLLAND BV 发明人 THROSBY MARK;CECILIA A W GEUIJEN;DE KRUIF CORNELIS ADRIAAN
分类号 C12N15/09;A61K39/395;A61K45/00;A61P31/04;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/02;C12P21/08 主分类号 C12N15/09
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