发明名称 |
TRANSDERMAL THERAPEUTIC SYSTEM FOR EXTENDED DOSING OF PRAMIPEXOLE IN TREATING NEUROLOGICAL DISORDERS |
摘要 |
This disclosure relates to a transdermal therapeutic system (TTS) containing pramipexole or related compounds and methods of making the system as well as its use in administering such compounds as a single dose over an extended period, for example, one week. The system comprises an acrylic-based or silicone-based matrix layer containing pramipexole at concentrations of at least about 5 wt.% of the matrix, which is resistant to crystallizing and discoloration of the active ingredient even when stored over long periods. |
申请公布号 |
WO2014188329(A2) |
申请公布日期 |
2014.11.27 |
申请号 |
WO2014IB61545 |
申请日期 |
2014.05.19 |
申请人 |
MYLAN, INC. |
发明人 |
DESHMUKH, ABHIJIT MUKUND;DIXIT, AKHILESH;KUMAR, PRASANNA;BINDRA, VIKRAM |
分类号 |
A61K9/70 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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