This invention provides an examination method whereby cell membranes in a biological material can be examined using optics that do not require rigorously precise design. Said examination method, which is used to examine specimens containing cell membranes, has the following steps: a step (a) in which a light-intensifying element that has a substrate, an intensifying-electromagnetic-field formation layer in which a large number of separate metal microparticles are dispersed across the surface of the substrate, and a protective layer formed on top of the substrate and the intensifying-electromagnetic-field formation layer is prepared; a step (b) in which a specimen to be examined is placed on the top surface of the protective layer; a step (c) in which the light-intensifying element is exposed to excitation light; and a step (d) in which light emitted from the specimen is received and the emission spectrum thereof is measured.
申请公布号
WO2014188621(A1)
申请公布日期
2014.11.27
申请号
WO2013JP81663
申请日期
2013.11.25
申请人
USHIO DENKI KABUSHIKI KAISHA;KYOTO UNIVERSITY;KYOTO PREFECTURAL UNIVERSITY OF MEDICINE