发明名称 |
FUSION PROTEINS FOR TREATMENT OF CNS |
摘要 |
PROBLEM TO BE SOLVED: To provide compositions capable of use in treatment of spinal cord injuries and related disorders of the central nervous system (CNS).SOLUTION: This invention relates to compositions including at least two of a protein transduction domain, a proteoglycan degrading domain, and a domain capable of blocking and/or coming over the activity of neuronal growth inhibitory molecules. Any two domains of the polypeptide are together linked to a linker polypeptide domain. |
申请公布号 |
JP2014221793(A) |
申请公布日期 |
2014.11.27 |
申请号 |
JP20140138911 |
申请日期 |
2014.07.04 |
申请人 |
ACORDA THERAPEUTICS INC |
发明人 |
GRUSKIN ELLIOTT A;CAGGIANO ANTHONY O;JENNIFER IACI;ZIMBER MICHAEL P;ROY GARGI |
分类号 |
A61K38/00;A61K;A61K31/00;A61K35/12;A61K38/43;A61K38/46;A61K45/00;A61P25/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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