MATERIALS AND METHODS FOR DETECTING AND/OR PREDICTING NECROTIZING ENTEROCOLITIS IN INFANTS

摘要

The subject invention pertains to materials and methods for diagnosing and/or predicting pathologic infant conditions. A method of the invention comprises obtaining a biological sample from an infant and analyzing the sample to detect at least one protein biomarker of necrotizing enterocolitis (NEC), wherein a patient is diagnosed with NEC or determined to have a likelihood of developing NEC following detection of the biomarker. In another method of the invention, the likelihood of a patient developing NEC is determined. In certain embodiments, treatment is administered to the patient following diagnosis of NEC or determination that the patient has a likelihood of developing NEC.

主权项

1. A method for diagnosing necrotizing enterocolitis (NEC) in an infant, wherein said method comprises: (a) obtaining a buccal sample from an infant patient; (b) analyzing the sample to detect at least one protein biomarker of NEC; and, based on the detection of the at least one protein biomarker, (c) diagnosing NEC in the patient.