| 发明名称 |
1-(2-FLUOROBIPHENYL-4-YL)-ALKYL CARBOXYLIC ACID DERIVATIVES FOR THE THERAPY OF TRANSTHYRETIN AMYLOIDOSIS |
| 摘要 |
<p>Derivatives of 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid are capable of stabilizing the tetrameric native state of transthyretin for the prophylaxis and treatment of amyloidosis.</p> |
| 申请公布号 |
EP2560942(B1) |
申请公布日期 |
2014.11.26 |
| 申请号 |
EP20110723282 |
申请日期 |
2011.04.19 |
| 申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
IMBIMBO, BRUNO PIETRO;VILLETTI, GINO;BERNI, RODOLFO |
| 分类号 |
C07C57/58;A61K31/19;A61P25/28;A61P43/00 |
主分类号 |
C07C57/58 |
| 代理机构 |
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